Definition. Adult and adolescent onset muscular dystrophies (MDs) are a group of disorders that cause muscle disease (myopathy) characterized by progressive muscle weakness (myasthenia) and muscle degeneration (atrophy) due to mutations in one . The CTG repeat size in adult onset is generally in the range of 50 to 1,000. 1 The mild form of DM1 is characterized by mild weakness, myotonia, and cataracts. Age at onset is between 20 and 70 years (typically onset occurs after age 40), and life expectancy is normal.
Muscular Dystrophy in Adults. This issue and weakness is because of the absence of a protein called dystrophin, which is needed for typical muscle function. The absence of this protein can cause problems with walking, swallowing, and muscle coordination. There are more than 30 various kinds of muscular dystrophies, which differ in symptoms and intensity. Facioscapulohumeral muscular dystrophy affects the muscles of the face, shoulders, and upper arms. It can affect anyone from teenagers to adults in their 40s. Distal muscular dystrophy affects the muscles of the arms, legs, hands, and feet. It usually comes on later in life, between ages 40 and 60.Author: Stephanie Watson.
Muscular Dystrophy -- Late Onset: Introduction. Muscular Dystrophy -- Late Onset: Muscle weakness and wasting that occurs later in life. The severity is variable with severe cases involving wheelchair confinement and death can occur if the heart muscle becomes involved. Progression may . Limb-girdle muscular dystrophy affects both males and females. Most people with this form of muscular dystrophy are disabled by age 20. However, many have a normal life expectancy.Author: Janelle Martel.